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Effect of flavored on!® nicotine pouch products on smoking behaviors: A sequential, multiple assignment, randomized controlled trial.

Karelitz JL, Rose JE, Kennedy JN, Freehauf C, Willette PN, Cohen G, Botts DR, Botts TL, Largo EG, Richter N, Lama S, Cheng HG · Drug and alcohol dependence, 2026

nicotine-pouchcombustible

This study tested whether nicotine pouches with flavors help people reduce cigarette smoking compared to unflavored versions. Both flavored and unflavored pouches helped smokers cut cigarette use by about half, though flavors may help non-responders and create more smoke-free days initially.

Relevance to India: None stated.